At the age of seventeen she wrote her first essay, a commentary on the analysis of the conic sections of the French mathematician de L'Hôpital, and a few years later, in 1738, she published a collection of essays on philosophy, mathematics and physics, "Propositiones philosophicae", in which she also touched on the issue of female education.
Mathematics is her greatest "entertainment", as she puts it. ".... lead us safely to the truth and to contemplate it, than which nothing is more pleasant", and more specifically the "Instituzioni Analitiche ad uso della gioventù italiana", two volumes of over a thousand pages whose composition Maria Gaetana follows.
On the book, the French Academy of Sciences wrote, "We consider it the most complete and best accomplished treatise", and Pope Benedict XIV, in 1750, gave her a crown of precious stones bound in gold, a gold medal and the chair of mathematics at the University of Bologna.
After her father's death, Agnesi divided the inheritance, organizes a hospital at home and to finance it sells the trousseau and diamonds, a gift from the empress.
Maria Gaetana died in 1799. By her will, she was buried in a mass grave.







